Which Resident Evil game was the first to use the RE Engine?

Resident Evil 7: Biohazard was the first Resident Evil game to use the RE Engine.

Capcom developed the RE Engine for Resident Evil 7: Biohazard, which made it the engine's first Resident Evil release. The technology supported detailed environments, realistic character models, and the game's close first-person presentation inside the Baker family's Louisiana property.

The engine later became the foundation for several Capcom projects, including Resident Evil 2, Resident Evil 3, Resident Evil Village, and the 2023 remake of Resident Evil 4. This shared technology helps explain visual and technical similarities among those games, although each title has its own art direction and gameplay systems.

A common mix-up is to name Resident Evil Village because that game prominently uses the engine and was released after Capcom had refined it. Village was not the first; Resident Evil 7 introduced the engine to the series in 2017.