The Rage virus causes the outbreak in the 2007 film 28 Weeks Later.
28 Weeks Later is the sequel to 28 Days Later and takes place after the initial outbreak in Britain. The infection is called the Rage virus because it produces extreme aggression and violent behavior in infected people. It is not presented as a conventional reanimation disease: victims are living humans whose behavior is transformed by infection.
The sequel follows children Andy and Tammy as they return to London during an attempt to repopulate and secure the city. Their father, Don, is involved in the family’s dangerous reunion, while military authorities struggle to contain renewed transmission.
The film was directed by Juan Carlos Fresnadillo, with a story by Rowan Joffe, Enrique López Lavigne, and Jesús Olmo. The original film’s director, Danny Boyle, served as an executive producer. The Rage virus is also referenced in the wider fictional continuity associated with 28 Days Later.