The James Bond film featuring the fictional Caribbean island of Crab Key is Dr. No.
Crab Key is the private island of the film’s antagonist, Julius No, a reclusive scientist and agent of SPECTRE. Bond travels there while investigating the disappearance of British intelligence operative John Strangways in Jamaica. The island becomes the setting for the film’s climax, including Bond’s confrontation with Dr. No and the destruction of the villain’s nuclear monitoring facility.
Dr. No, released in 1962, was the first film in Eon Productions’ official James Bond series and starred Sean Connery as 007. The story adapts Ian Fleming’s 1958 novel of the same name, although the film changes several details and locations. Crab Key is fictional, but the production used Jamaican locations to create the film’s Caribbean atmosphere.
Crab Key is sometimes confused with other Bond villains’ island bases, such as San Monique in Live and Let Die or Emilio Largo’s underwater headquarters in Thunderball.