Chemical X accidentally creates the girls’ superpowers in The Powerpuff Girls.
Professor Utonium’s recipe calls for sugar, spice, and everything nice, but an unexpected splash of Chemical X changes the experiment. The result is the birth of Blossom, Bubbles, and Buttercup, each with extraordinary abilities.
Chemical X is one of the show’s central pieces of fictional science. It explains both the trio’s powers and several later stories involving mutations, transformations, and superpowered characters. The substance is not presented as a real chemical or a scientifically plausible compound.
Viewers sometimes confuse Chemical X with Chemical Z, which appears in the franchise’s Japanese anime spin-off Powerpuff Girls Z. The original American series uses Chemical X.