House M.D. first premiered in the United States on the Fox network.
The series debuted on November 16, 2004, and was developed for Fox by David Shore. Its procedural format followed Dr. Gregory House and his team as they investigated unusually difficult medical cases.
Fox positioned the program as a medical drama with a distinctive mystery structure. Each episode typically presented a puzzling illness, included competing diagnostic theories, and used tests and observations to narrow the possibilities.
The show became one of Fox’s signature scripted programs during the 2000s. It eventually ran for eight seasons, ending in 2012. International broadcasters often used the shorter title House, while House M.D. was the familiar title in several markets.