In Assassin's Creed Syndicate, London is the main setting for Jacob and Evie Frye's story.
The game is set in London during the Industrial Revolution, primarily in 1868. The Frye twins arrive to challenge Templar control over the city and build an Assassin gang called the Rooks. Their campaign moves through districts that include Westminster, the City of London, Southwark, Lambeth, and the Strand.
Syndicate combines historical figures with fictional characters and events. Queen Victoria, Charles Dickens, and Alexander Graham Bell appear in the game, while Jacob and Evie pursue separate missions reflecting their different approaches. The setting is Victorian London rather than another British industrial city.