The original animated series The Powerpuff Girls had six seasons.
The series ran on Cartoon Network from 1998 to 2005 and was organized into six seasons. Across that run, it followed Blossom, Bubbles, and Buttercup as they balanced kindergarten life with defending Townsville from villains and disasters. The show’s short, self-contained stories made it possible for episodes to be watched independently, which can make season boundaries less obvious to casual viewers.
The original production is often described as having 78 episodes, although many broadcasts presented separate story segments within half-hour programming blocks. This packaging is one reason episode totals can look different across reference sources. Season counts are clearer: the original television run is conventionally listed as six seasons.
The later 2016 reboot is a separate series and should not be added to the original show’s season total. The 2002 theatrical film also does not count as a seventh season; it is a standalone feature connected to the same franchise.