Which UK institute sequenced a major portion of the human genome?

The Wellcome Sanger Institute sequenced a major portion of the human genome. Based in Hinxton, Cambridgeshire, it was a major British sequencing centre and made the largest single contribution to the reference sequence produced by the Human Genome Project.

The institute was established in 1992 as the Sanger Centre and opened during the early years of the international project. It was funded primarily by the Wellcome Trust and named after Frederick Sanger, the British scientist who won two Nobel Prizes. The centre later became the Wellcome Trust Sanger Institute and then the Wellcome Sanger Institute.

Sanger researchers collaborated on sequencing eight of the 23 human chromosome pairs: chromosomes 1, 6, 9, 10, 13, 20, 22 and X. That contribution helped create the high-quality reference sequence published in 2004. Its work also supported the project’s strong commitment to rapid public data sharing.

A common mix-up is choosing the Broad Institute or EMBL. Both are major genomics organisations, but the question asks for the UK institute associated with a substantial share of the Human Genome Project’s sequencing work.