Which DOE official outlined a broad HGP plan in a memo to Alvin Trivelpiece?

The DOE official who outlined a broad Human Genome Project plan in a memo to Alvin Trivelpiece was Charles DeLisi.

DeLisi was director of the Department of Energy’s Health and Environmental Research Programs during the crucial early planning period. His memo to Trivelpiece, then an assistant secretary for energy research, described a large-scale effort to map and sequence human DNA and helped move the proposal through DOE’s leadership.

Trivelpiece supported the proposal and sought approval to redirect about $4 million in 1986 funds to initiate the work. Deputy Secretary William Flynn Martin and other DOE officials became important allies, while Senator Pete Domenici later helped the project gain congressional backing.

The other options held significant later roles but were not the official who wrote this foundational memo. Martin was a senior DOE policymaker, Aristides Patrinos later led DOE genome efforts, and David Galas directed the renamed biological research office in the 1990s.