Which Star Trek film features the first appearance of the USS Enterprise-E?

Star Trek: First Contact features the first appearance of the USS Enterprise-E.

The Enterprise-E is the Sovereign-class starship commanded by Jean-Luc Picard in the film. It replaced the Galaxy-class USS Enterprise-D, which was destroyed during the events of Star Trek: Generations. First Contact therefore begins a new ship era for the Next Generation film crew.

The Enterprise-E is sent to confront the Borg in the 24th century, but the Borg use time travel to attack Earth in the past. The ship follows them through a temporal vortex and becomes involved in humanity's first contact with the Vulcans. Its sleek design was created for the film and later appeared in Star Trek: Insurrection and Star Trek: Nemesis.

The ship is sometimes confused with the Enterprise-D because both are associated with Picard. The Enterprise-D remains central to The Next Generation television series and is seen in the earlier film, while the Enterprise-E is the principal ship of the final three Next Generation movies.