Cleopatra VII is the historical queen who becomes the central ally of Bayek and Aya in Assassin's Creed Origins.
Set in Ptolemaic Egypt, Origins depicts Cleopatra competing with her brother Ptolemy XIII for control of the kingdom. Bayek and Aya initially support Cleopatra because the Order of the Ancients backs forces threatening her position. Their alliance brings the protagonists into the political and military conflicts surrounding Alexandria and Egypt.
The game uses real historical figures alongside fictional characters and fictionalizes events for its larger story. Cleopatra's relationship with Julius Caesar and the struggle against the Order are dramatized within the game's narrative.
Cleopatra VII is distinct from earlier Egyptian queens such as Nefertiti and Hatshepsut. Berenice II was also a Ptolemaic queen, but she lived generations before the period portrayed in Origins.