Which Beyoncé song features Jay-Z and opens with the horn-driven hook “Uh-oh”?

Beyoncé’s song featuring Jay-Z and opening with the “Uh-oh” hook is “Crazy in Love.”

Released in 2003, the song was the lead single from Beyoncé’s debut solo album, Dangerously in Love. It prominently samples the horn section from the Chi-Lites’ 1970 song “Are You My Woman (Tell Me So),” creating its instantly recognizable opening.

Jay-Z contributes a rap verse, while Beyoncé sings about the overwhelming feeling of falling in love. The single topped the Billboard Hot 100 and became one of Beyoncé’s signature recordings. Its music video, directed by Jake Nava, also became closely associated with the song’s visual identity.

“Crazy in Love” is sometimes mixed up with “Drunk in Love,” another Beyoncé and Jay-Z collaboration released years later. The two songs share the couple’s voices, but only “Crazy in Love” contains the famous sampled horn introduction and appears on Dangerously in Love.