Which Assassin's Creed title was the first to use the series' modern-day protagonist Layla Hassan?

Assassin's Creed Origins was the first Assassin's Creed title to use Layla Hassan as its modern-day protagonist.

Layla is an Abstergo researcher who develops an unauthorized Animus device and uses it to examine the memories of Bayek and Aya. Her work in Origins places her outside the company's approved research structure and draws her into the modern Assassin-Templar conflict.

She remains important in later games, including Assassin's Creed Odyssey and Assassin's Creed Valhalla. This continuity makes her different from Desmond Miles, who anchors the modern-day stories of the earlier major entries.

The historical hero of Origins is Bayek of Siwa, while Layla occupies the contemporary storyline. Confusing those roles can produce an answer that names Bayek even though the question asks specifically about the modern-day protagonist.