Which Assassin's Creed game follows Altaïr's later life in Constantinople?

Assassin's Creed: Revelations follows Altaïr's later life in Constantinople through Ezio's memories.

The game is primarily set in Constantinople during the early sixteenth century, where the older Ezio searches for Altaïr's lost keys and investigates the history of the Assassin Brotherhood. These keys unlock memories of Altaïr at several stages of his life.

Revelations therefore connects two major protagonists rather than presenting only one historical storyline. It also concludes Ezio's personal arc, which began in Assassin's Creed II and continued through Brotherhood.

The game includes a fictionalized version of Constantinople, with districts on both sides of the Golden Horn. Its story features Ottoman figures including Prince Suleiman, who later became Sultan Suleiman the Magnificent.