Which Assassin's Creed game first featured a female protagonist named Aveline de Grandpré?

Assassin's Creed III: Liberation first featured Aveline de Grandpré as a playable female protagonist.

Liberation was released for the PlayStation Vita in 2012. Aveline is a Louisiana-born Assassin of French and African heritage who operates in New Orleans and surrounding areas during the eighteenth century. Her campaign overlaps historically with the era of Assassin's Creed III but follows its own story.

Aveline uses three disguises—Lady, Slave, and Assassin—to approach missions in different ways. Each identity affects her available equipment, social access, and combat options. This disguise system is central to both the gameplay and the story's exploration of race, class, and colonial society.

Later games offered other prominent female protagonists, including Evie Frye in Syndicate and Kassandra as a selectable protagonist in Odyssey. Aveline's appearance in Liberation predates those releases and made the handheld title an important entry in the franchise's character history.