Which ancient city is the main setting for Ezio's story in Assassin's Creed Revelations?

Constantinople is the main setting for Ezio's story in Assassin's Creed Revelations.

Ezio travels to Constantinople in 1511 to search for keys connected to Altaïr's library in Masyaf. The city is divided into districts associated with the Byzantine and Ottoman worlds, and Ezio works with local Assassins led by Yusuf Tazim. The game also includes the nearby Cappadocia sequence.

Constantinople was the capital of the Byzantine Empire until its Ottoman conquest in 1453. By the time of the game, it is the capital of the Ottoman Empire under Sultan Bayezid II and later his son Selim I. This setting allows the story to connect Ezio's Renaissance journey with Altaïr's earlier life.

The city is often called Istanbul today, but Constantinople is the historical name used for the game's 1511 setting. The game begins in Masyaf and includes modern-day Animus sequences, yet Constantinople remains Ezio's principal historical base.