What is the title of the 2009 game that continues Ezio Auditore's story in Renaissance Italy?

Assassin's Creed II is the 2009 game that introduces and continues Ezio Auditore's story in Renaissance Italy.

Ubisoft released the game in November 2009. It moves the series from the first game's Crusades setting to fifteenth-century Italy, with major locations including Florence, Monteriggioni, Venice, and Forlì. Ezio's personal quest develops alongside a larger conflict between the Assassins and Templars.

The game expanded the original formula with more weapons, businesses, equipment, and opportunities for exploration. It also introduced Leonardo da Vinci as an important ally who helps Ezio understand and use specialized devices.

Brotherhood is the direct sequel set mainly in Rome, while Revelations later concludes Ezio's main story in Constantinople. Those titles are often discussed together as the Ezio trilogy, but Assassin's Creed II is the first of the three.