What is the name of the only Star Trek series set entirely on a space station?

The only Star Trek series set entirely around a space station is Star Trek: Deep Space Nine. Its central location is the station Deep Space Nine, positioned near the planet Bajor and the entrance to a stable wormhole.

The station began as Terok Nor, a Cardassian mining and refinery facility built by Bajoran forced labor during the Cardassian occupation. After the occupation ended, Bajor requested Federation assistance, and the station was renamed Deep Space Nine. Commander Benjamin Sisko was assigned to lead its mixed Starfleet and Bajoran administration.

Unlike the Enterprise or Voyager, Deep Space Nine is not primarily a starship-exploration show. The station serves as a diplomatic center, commercial hub, military outpost, and gateway to the Gamma Quadrant. The USS Defiant later gave its crew a dedicated small starship for missions away from the station.

“Entirely” describes the series’ defining setting rather than every scene: characters do travel to planets and other ships. Enterprise is a starship series, Voyager follows a stranded starship, and The Next Generation centers on the Enterprise-D.