What is the name of the fictional artifact central to Assassin's Creed: Brotherhood?

The fictional artifact central to Assassin's Creed: Brotherhood is the Apple of Eden. It is one of the Pieces of Eden, powerful devices created by the ancient Isu civilization in the series' mythology.

In Brotherhood, Ezio Auditore seeks to protect the Apple while opposing Cesare Borgia and the Templar Order in Renaissance Rome. The artifact can influence minds and reveal information, making it a major source of conflict between the Assassins and Templars.

The Apple is not the same as every other Piece of Eden. The series also features artifacts such as the Staff, Sword, and Shroud, each with different histories and abilities. Brotherhood continues the story from Assassin's Creed II and was released in 2010, with Rome serving as its principal historical setting.