What is the name of the Assassin's Creed II city that serves as Ezio's home base?

Monteriggioni is the city that serves as Ezio's home base in Assassin's Creed II.

Ezio reaches Monteriggioni after the early events in Florence, and the Auditore family villa there becomes a major headquarters. Players can renovate the settlement, improve its facilities, and earn income as the story progresses. The villa also functions as a place where Ezio can return between missions and display collected items.

The game presents Monteriggioni as a fortified hill town in Tuscany. Its fictionalized representation is connected to the real medieval town of Monteriggioni, known for its ring of defensive towers. The location gives the game a persistent base-management element alongside its urban missions.

Florence and Venice are also important Assassin's Creed II settings, but neither is Ezio's principal upgradeable home base. Forlì is another Italian location visited during the story. These locations are therefore plausible alternatives, while Monteriggioni specifically identifies the Auditore stronghold.