What highway is the fictional town of Radiator Springs located on in Pixar's Cars?

In Pixar's Cars, the fictional town of Radiator Springs is located on U.S. Route 66.

The setting reflects the historic American highway that once connected Chicago and Santa Monica. Route 66 became famous for roadside businesses, motels, service stations and small communities, many of which declined after newer interstate highways diverted traffic. Cars uses that history as the foundation for Radiator Springs, whose businesses have suffered after Interstate 40 bypassed the town.

Lightning McQueen reaches Radiator Springs after accidentally damaging the road and being required to repair it. The town's residents, including Sally Carrera and Doc Hudson, gradually teach him to value community over publicity and racing success.

The film's Route 66 connection is also visible in its visual design and music. Pixar artists researched the road and its landmarks while developing the movie. Radiator Springs is fictional, but its cultural identity is closely tied to the real highway and its roadside heritage.