What city is Arcane primarily set in alongside Zaun?

Arcane is primarily set in Piltover alongside Zaun.

The series centers on the relationship and conflict between these two connected cities in the League of Legends universe. Piltover is a wealthy, technologically advanced city, while Zaun is its oppressed underground counterpart, shaped by industrial pollution, poverty, crime, and political marginalization.

That geographic divide drives the stories of Vi, Powder—later known as Jinx—and many other major characters. Hextech development in Piltover intensifies tensions with Zaun, whose chemtech industries and independence movement challenge Piltover’s authority.

Viewers sometimes mistake Ionia, Noxus, or Demacia for the setting because all are important League regions. They are not Arcane’s primary location: Noxus becomes relevant through characters such as Ambessa Medarda, while the show’s central action remains focused on Piltover and Zaun. Arcane was created for television by Christian Linke and Alex Yee and premiered on Netflix in 2021.