Assassin’s Creed Syndicate is primarily set in 1868.
The game takes place in London during the Industrial Revolution. Players follow twin Assassins Jacob and Evie Frye as they fight Templar influence, criminal gangs, and exploitative industrial power. Factories, railways, crowded neighborhoods, and rapid technological change define the game’s version of Victorian London.
Syndicate was released in 2015, but its story occurs more than a century earlier, in the nineteenth century. That distinction matters because release dates and historical settings are often confused in Assassin’s Creed questions. The game’s principal year, 1868, places it after the French Revolution setting of Unity and before the twentieth-century events depicted in later franchise material.
The London setting includes historical figures such as Queen Victoria, Charles Dickens, and Alexander Graham Bell. These figures appear alongside fictional characters and missions. The game’s protagonists are Jacob and Evie Frye, but this answer concerns the historical year of the story rather than the game’s release year.