In the 2021 Czech census, which region was least populous?

In the 2021 Czech census, Karlovy Vary Region was the least populous Czech region, with 279,103 residents.

Karlovy Vary Region lies in the country’s far west, bordering Germany. It is named after Karlovy Vary, the internationally known spa city also called Carlsbad. The region’s population is spread among smaller towns and rural areas, and it lacks a city on the scale of Prague or Brno.

The 2021 census was carried out from 27 March to 9 April by the Czech Statistical Office, during the COVID-19 era. Central Bohemian Region was the most populous, with 1,415,463 residents. The question concerns administrative regions, not historic lands or individual municipalities, so Karlovy Vary’s status as the least populous region should not be confused with the population ranking of its namesake city.