House M.D. ran for eight seasons, airing from 2004 until 2012.
The medical drama premiered on Fox on November 16, 2004, and concluded with its series finale, “Everybody Dies,” on May 21, 2012. Across its run, the show followed House and changing teams of doctors as they tackled unusual diagnostic puzzles.
Its cast and format changed over time. Several original fellows left or moved into different roles, while new doctors joined House’s department. The final season introduced additional characters and storylines while still centering on House’s medical work and personal relationships.
Eight seasons is distinct from the show’s episode count, which is much larger. A season is a television-production grouping, not a count of years in which every episode necessarily aired continuously.