What song was used as House M.D.'s main title theme in its original U.S. broadcast?

“Teardrop” by Massive Attack was used as House M.D.'s main title theme in its original U.S. broadcast.

The song comes from Massive Attack's 1998 album Mezzanine. Its distinctive vocal performance was recorded by Elizabeth Fraser of the Cocteau Twins, whose voice helped make the track especially recognizable. The opening credits paired the music with stylized medical and anatomical imagery.

International versions and some later broadcasts could use different music because of licensing arrangements. That variation explains why viewers do not always remember the same theme. Another Massive Attack song, “You Know What I Mean,” was also associated with the program in some contexts, but “Teardrop” is the canonical original U.S. title theme.