In Assassin's Creed Origins, Alexandria serves as Cleopatra's main base. The game is set in Ptolemaic Egypt during the first century BCE, when Alexandria was a major Mediterranean capital and a center of scholarship, commerce, and royal power. Cleopatra uses the city while opposing her brother Ptolemy XIII and seeking political support.
Alexandria gives Origins some of its most recognizable urban locations, including the Great Lighthouse, the Library district, royal quarters, and the Pharos island area. The city contrasts with the deserts, villages, temples, and farming communities that Bayek visits elsewhere in Egypt.
Players may confuse Alexandria with Siwa, where Bayek begins the game, or Memphis, another major Egyptian city featured in the campaign. Siwa is Bayek's homeland and the setting for the opening conflict; Alexandria is the cosmopolitan political center connected to Cleopatra and the wider struggle against the Order of the Ancients.
The historical Alexandria was founded by Alexander the Great in 331 BCE. Its famous lighthouse was one of the ancient world's celebrated monuments, although the game presents a dramatic reconstruction rather than a complete archaeological record.