In Assassin's Creed Liberation, who is the first female protagonist of a standalone Assassin's Creed game?

Aveline de Grandpré is the first female protagonist of a standalone Assassin's Creed game.

Aveline leads Assassin's Creed III: Liberation, which was originally released for PlayStation Vita in 2012. She is a Louisiana-born Assassin of French and African heritage, and her story is set in eighteenth-century New Orleans and surrounding areas during the period of Spanish rule and revolutionary conflict.

Aveline uses disguises as part of her gameplay identity. Her available personas include a Lady, a Slave, and an Assassin, each offering different movement options, social access, equipment, and restrictions. The disguise system reflects both the game's stealth design and the social conditions of its historical setting.

Other important women in the franchise include Elise de la Serre in Unity, Evie Frye in Syndicate, and Kassandra in Odyssey. They are not the answer because their games came later or give them a different narrative role. Liberation's original handheld release was later followed by versions on additional platforms.