In Assassin's Creed Liberation, Aveline's story is mainly set in New Orleans.
The game follows Aveline de Grandpré, a Franco-African Assassin active in Louisiana during the eighteenth century. New Orleans is the principal urban setting, and the player explores its streets, districts, docks, and surrounding areas while investigating the activities of the Templars and other factions.
Liberation was originally released for the PlayStation Vita in 2012 as a companion title to Assassin's Creed III. Its setting links it to the broader colonial-era world of the series, but Aveline's perspective and identity give the game a distinct narrative. The story also includes locations beyond New Orleans, including the Louisiana bayou and Chichén Itzá.
Havana is the central Caribbean city in Assassin's Creed IV: Black Flag, while Boston is a major setting in Assassin's Creed III. Alexandria is the principal city associated with Assassin's Creed Origins, not Liberation.