In Assassin's Creed II, the Palazzo della Signoria landmark is located in Florence.
Florence is one of the principal cities explored by Ezio Auditore during the opening and later sections of the game. The Palazzo della Signoria, also known as the Palazzo Vecchio, appears as a major political and architectural landmark in the game's Renaissance setting.
The real Palazzo Vecchio stands in Florence's Piazza della Signoria and has served as the city's town hall for centuries. Its distinctive medieval appearance makes it one of Florence's most recognizable buildings. Assassin's Creed II places fictional missions and characters around this authentic urban environment.
Players sometimes confuse Florence with Venice because both cities are major settings in Assassin's Creed II. Venice contains landmarks such as the Basilica di San Marco and the Rialto Bridge, whereas the Palazzo della Signoria belongs to Florence. The game also includes Monteriggioni and Forlì, but neither is the city associated with this palace.