In Assassin's Creed Brotherhood, which Roman landmark becomes Ezio Auditore's headquarters?

In Assassin's Creed Brotherhood, Ezio Auditore's headquarters is the Assassin hideout on Tiber Island.

Tiber Island lies in the Tiber River in central Rome and becomes the operational base for Ezio and the Roman Assassin Brotherhood. From there, players can manage recruits, access equipment and training, and coordinate the campaign against the Borgia family. The hideout is linked to the broader rebuilding of the Brotherhood after its defeat in Monteriggioni.

The location should not be confused with the Colosseum or Castel Sant'Angelo, which are major Roman landmarks and mission locations but are not Ezio's principal headquarters. Brotherhood was released in 2010 and continues Ezio's story after Assassin's Creed II. Its Rome setting also introduces the ability to recruit and train new Assassins, making the headquarters important both narratively and mechanically.