Who played Dean of Medicine Lisa Cuddy in House M.D.?

Lisa Edelstein played Lisa Cuddy in House M.D. Cuddy is the dean of medicine and hospital administrator who supervises House at Princeton–Plainsboro Teaching Hospital.

Cuddy repeatedly protects the hospital's diagnostic department while also trying to control House's rule-breaking, drug use, and confrontational behavior. Her authority creates an institutional counterweight to House's medical independence. The character's professional relationship with House later becomes romantic, adding another layer of conflict to their long-running partnership.

Edelstein appeared as a main cast member for the first seven seasons. Cuddy's departure is addressed at the end of the seventh season, and the hospital's leadership changes in the final season. Edelstein's performance made Cuddy one of the show's most recognizable administrators.