What medical specialties does Dr. House practice in House M.D.?

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Dr. Gregory House practices infectious disease and nephrology in House M.D.

House’s dual specialties explain why he is especially interested in systemic illnesses, infections, kidney disorders, and diagnostic puzzles that cross ordinary departmental boundaries. He leads the hospital’s Department of Diagnostic Medicine, where his team investigates cases that remain unexplained after routine consultations.

Infectious disease focuses on illnesses caused by pathogens and on conditions that spread between people or affect the body systemically. Nephrology focuses on the kidneys, including kidney function, fluid balance, blood pressure, and related disorders. House’s medical knowledge allows him to move between these fields while searching for an underlying cause.

The show often dramatizes House as if he were a general expert in every medical field. In reality, physicians usually consult colleagues with different specialties. House’s diagnostic role is deliberately exceptional, and the series uses that fictional structure to make complex cases accessible to viewers.

Source: Wikipedia · fact-checked Oct. 2026

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