Alfred Stieglitz operated the New York gallery known as 291 when he first exhibited Georgia O'Keeffe's drawings.
The gallery was officially called the Little Galleries of the Photo-Secession and was located at 291 Fifth Avenue in Manhattan. Its short name, 291, came from the street address. Stieglitz used the space to show photography and then to introduce American audiences to European modern art.
In 1916, Stieglitz exhibited a group of O'Keeffe's abstract charcoal drawings at 291. The show helped launch her professional reputation in New York, even though she was then teaching in Texas and had not yet met Stieglitz personally.
Later, Stieglitz ran other galleries, including the Intimate Gallery and An American Place. Those names are sometimes mixed up with 291, but the earliest O'Keeffe exhibition connected to him took place at 291.