Which main-series film lacks Vin Diesel as Dominic Toretto?

The main-series film that lacks Vin Diesel as Dominic Toretto is 2 Fast 2 Furious.

Released in 2003, 2 Fast 2 Furious follows Brian O’Conner in Miami rather than Dominic’s Los Angeles-centered crew. Paul Walker returns as Brian, who teams up with his estranged childhood friend Roman Pearce to infiltrate the operation of drug lord Carter Verone. Vin Diesel was offered a substantial fee to return, but he declined after deciding the screenplay was not strong enough.

This answer is often mixed up with The Fast and the Furious: Tokyo Drift. Dom does not drive the story of Tokyo Drift, but Vin Diesel appears as Dominic in a cameo at the end. That appearance means Tokyo Drift is not the main-series film completely lacking Diesel’s Dominic. Furious 7 and Fast Five both feature Dom prominently.

The franchise later used the short film The Turbo Charged Prelude for 2 Fast 2 Furious to connect Brian’s escape from Los Angeles with his arrival in Miami. The sequel also introduced or expanded characters who became important later, especially Roman Pearce and Tej Parker.