Which historical era and region does Assassin's Creed Origins primarily depict?

Assassin's Creed Origins primarily depicts Ptolemaic Egypt.

The game is set mainly during the first century BCE, when Egypt was ruled by the Ptolemaic dynasty. Its protagonist, Bayek of Siwa, is a Medjay who becomes involved in the origins of the Hidden Ones, the organization that later develops into the Assassin Brotherhood.

The story includes major historical figures such as Cleopatra VII and Julius Caesar. Players travel through cities, villages, deserts, and ancient landmarks, including Alexandria and Memphis. The setting reflects Egypt's interaction with the Roman Republic and the continuing influence of Greek culture under the Ptolemies.

The title “Origins” refers to the fictional beginnings of the Assassin tradition rather than the literal founding of every later organization in history. The game also introduced a larger role-playing structure to the main series, including levels, equipment rarity, and ability trees.