Which character did Isabel Sanford play in season 5 episode 17?

Isabel Sanford played Louise Jefferson in season 5 episode 17 of The Fresh Prince of Bel-Air.

The episode, “Will Is from Mars,” features Will and Lisa attending counseling with George and Louise Jefferson. Sanford therefore appears as Louise, the matriarch of the classic sitcom The Jeffersons, rather than as one of the Banks family’s regular relatives.

The appearance was part of a crossover-style meeting between two major television families. Sherman Hemsley reprised George Jefferson, Louise’s husband, while the characters participate in a couples-therapy setting. The scene uses the Jeffersons’ long-established personalities while placing them in Fresh Prince’s comedy framework.

Sanford had played Louise Jefferson for more than a decade before this guest appearance. The Jeffersons began in 1975 as a spin-off from All in the Family and ran for 11 seasons, ending in 1985. Sanford’s return as Louise helped link Fresh Prince to an earlier generation of influential Black television sitcoms.