Which bacterium causing gonorrhoea did Fleming find was affected by penicillin?

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The bacterium causing gonorrhoea that Fleming found was affected by penicillin was Neisseria gonorrhoeae.

Fleming tested penicillin’s activity against numerous organisms after observing that a Penicillium mould inhibited staphylococci. Penicillin worked especially well against many Gram-positive bacteria, but Fleming also recorded activity against N. gonorrhoeae, an important Gram-negative exception.

The finding mattered because gonorrhoea is caused by a specific bacterium, not by a virus or fungus. Neisseria gonorrhoeae is a diplococcus, meaning its cells typically appear in pairs under a microscope. The species name is the canonical scientific answer; “the gonococcus” is a common shorthand.

A modern complication is antibiotic resistance. Penicillin was once an effective treatment for gonorrhoea, but resistant strains became widespread, so contemporary therapy relies on other antibiotics and public-health guidance rather than Fleming’s original drug.

Source: Wikipedia · fact-checked Sept. 2026

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