The 2006 film directed by Alfonso Cuarón and set in a future where women are infertile is Children of Men.
The film takes place in 2027, after nearly two decades without a recorded birth. Clive Owen plays Theo Faron, a former activist who becomes involved in protecting Kee, a young refugee whose pregnancy could offer humanity its only hope.
Children of Men adapts P. D. James's 1992 novel The Children of Men, though the film changes important details. In the novel, the infertility is linked to male infertility; the film leaves the cause unexplained. That uncertainty reinforces its themes of social collapse, authoritarian government, refugee persecution, environmental damage, and faith.
Alfonso Cuarón co-wrote and directed the film, which is especially known for its immersive long takes and cinematography by Emmanuel Lubezki. The title is sometimes confused with the source novel's wording, but both refer to the same central crisis: a civilization with no children and no visible future.