Georgia O'Keeffe's New York gallery debut in 1916 took place at 291, Alfred Stieglitz's influential Manhattan gallery. The gallery's name came from its address at 291 Fifth Avenue.
Anita Pollitzer showed some of O'Keeffe's abstract charcoal drawings to Stieglitz, who exhibited them at 291 without first obtaining O'Keeffe's permission. O'Keeffe was initially upset, but the exhibition introduced her work to an important network of American modernists and helped establish her public career.
291 was founded by Stieglitz in 1905 as the Little Galleries of the Photo-Secession and was renamed for its address. It presented photography alongside modern European and American art. After 291 closed in 1917, Stieglitz later operated the Intimate Gallery and An American Place, but those were different venues and should not be confused with O'Keeffe's first New York showing.