291 was the New York gallery associated with Georgia O'Keeffe’s early career.
Alfred Stieglitz exhibited O'Keeffe’s abstract charcoal drawings at 291 in 1916. The gallery’s name came from its address at 291 Fifth Avenue in Manhattan. Those drawings were shown without her prior permission, but the exhibition brought her work to the attention of the New York art world.
The gallery was founded and directed by Stieglitz. It became an influential center for modern art and photography, presenting European artists such as Pablo Picasso, Henri Matisse, and Constantin Brancusi alongside American artists.
291 closed in 1917, but Stieglitz continued promoting O'Keeffe through later galleries. The name is sometimes confused with An American Place, the gallery he operated later in his life. O'Keeffe’s first important New York exposure belongs specifically to 291.