Alfred Stieglitz's New York gallery 291 first showed Georgia O'Keeffe's drawings in 1916.
The gallery was named for its address at 291 Fifth Avenue. Stieglitz used it to introduce American audiences to European modernism and to promote innovative American artists and photographers. Its exhibitions included work by figures such as Pablo Picasso, Henri Matisse, and Paul Cézanne.
Anita Pollitzer brought O'Keeffe's charcoal drawings to Stieglitz. He exhibited them at 291 without O'Keeffe's prior approval, and she initially objected. The exhibition nevertheless began the professional relationship that transformed her career.
291 closed in 1917, but Stieglitz continued supporting O'Keeffe through later galleries, including the Intimate Gallery and An American Place.