Georgia O'Keeffe first exhibited at Alfred Stieglitz's gallery 291 in 1916.
The gallery was located at 291 Fifth Avenue in New York City, which gave it the shortened name “291.” Stieglitz originally founded it as the Little Galleries of the Photo-Secession, but it became widely known by its address. It displayed photography alongside European and American modern art.
In 1916, Stieglitz showed a group of O'Keeffe's abstract charcoal drawings there. The exhibition was a turning point: it brought her work to the attention of an influential New York art circle and began a professional association that lasted for decades.
A common confusion is calling the venue An American Place, another Stieglitz gallery that opened later. Stieglitz also operated the Intimate Gallery after 291 closed, but O'Keeffe's first exhibition with him took place at 291.