Georgia O'Keeffe's first New York gallery connection through Alfred Stieglitz was 291, the gallery named for its address at 291 Fifth Avenue. Stieglitz founded it as the Little Galleries of the Photo-Secession before the shorter name became standard.
The gallery became an important meeting place for American modernism. Stieglitz showed photography alongside European and American avant-garde art, helping New York audiences encounter artists and ideas that challenged academic traditions.
O'Keeffe's abstract drawings were exhibited there in 1916, before she and Stieglitz married. The gallery's name is sometimes confused with Stieglitz's later spaces, including the Intimate Gallery and An American Place. Those were separate venues from different periods of his career, while 291 refers specifically to the Fifth Avenue gallery.