Georgia O'Keeffe's first major New York gallery was 291. The gallery was founded and operated by Alfred Stieglitz at 291 Fifth Avenue in Manhattan, and its name came from the building's street number.
Stieglitz first showed O'Keeffe's abstract charcoal drawings there in 1916. The exhibition marked her New York debut and introduced her work to a circle of artists, critics, and collectors interested in modern art.
The gallery had originally been called the Little Galleries of the Photo-Secession. It became widely known as 291 and presented photography alongside European modernism and innovative American art.
O'Keeffe's association with 291 was a major early step in her career, but she later exhibited at other Stieglitz venues, including The Intimate Gallery and An American Place. The number refers to the address, not an artwork title or a date.