The flower in Georgia O'Keeffe's Jimson Weed/White Flower No. 1 is jimson weed, a plant also known as Datura stramonium.
O'Keeffe painted the large white flower in 1932, enlarging its trumpet-like form until it fills much of the canvas. The image demonstrates her frequent practice of isolating natural forms and presenting them at an unexpectedly monumental scale.
Jimson weed is a common name for Datura stramonium, a plant in the nightshade family. It has attractive flowers but is poisonous, so the painting's beauty should not be mistaken for a statement that the plant is safe to handle or eat.
The work is sometimes confused with O'Keeffe's paintings of datura flowers from New Mexico. Those subjects are botanically related, and O'Keeffe repeatedly painted white trumpet-shaped blooms, but the specific title Jimson Weed/White Flower No. 1 identifies jimson weed.