The diagnostician protagonist’s surname is House: Dr. Gregory House.
Gregory House is the central character of House M.D. He leads teams that investigate rare and puzzling illnesses, often relying on observation, differential diagnosis, and unconventional tests or treatments.
The character’s surname is also a deliberate reference to Sherlock Holmes. Both characters are highly analytical, socially difficult, and skilled at solving mysteries by noticing details others overlook. House’s first name and initials, G.H., further support the show’s detective-story structure without making him a direct copy of Holmes.
House is portrayed as an exceptional physician whose leg injury causes chronic pain. He uses a cane and becomes dependent on pain medication, creating an ongoing conflict between his diagnostic abilities and personal health.