The fictional city protected by The Powerpuff Girls in the 2002 movie is Townsville.
Townsville is the main setting of the Powerpuff Girls franchise. It is portrayed as a modern city whose residents repeatedly face threats from villains such as Mojo Jojo, Fuzzy Lumpkins, and the Gangreen Gang.
The city also appears in the original television series and later adaptations. Its mayor frequently calls on the girls when danger threatens, although the trio often encounters trouble while trying to help ordinary citizens.
Pokey Oaks is not the city’s name: it is the kindergarten attended by the girls. The movie focuses on how the sisters were created and how they became Townsville’s defenders.