In which song does Madonna sings "Life is a mystery, Everyone must stand alone"?

Madonna sings "Life is a mystery, Everyone must stand alone" in "Like a Prayer."

The lyric appears near the beginning of the song, before the narrator sings about hearing someone call her name and feeling at home. Released in 1989, "Like a Prayer" became the title track of Madonna's fourth studio album and one of the defining singles of her career. Musically, it blends pop rock with gospel, funk and R&B elements, creating a sound that is both devotional and dramatic.

The song's religious language is deliberately layered. Its imagery can suggest prayer and spiritual calling, but commentators have also read romantic and sensual meanings into the lyrics. That ambiguity is one reason the song is often remembered as more than a straightforward religious pop song. A prominent gospel choir, led by Andraé Crouch, intensifies the spiritual atmosphere.

The question's wording is grammatically imperfect, but it does not affect the answer. A common mix-up is choosing "Live to Tell," another major Madonna song from the 1980s; its lyrics do not contain this opening line. "Like a Prayer" reached number one in several countries and remains among Madonna's signature recordings.