Georgia O'Keeffe lived and worked with Alfred Stieglitz in Manhattan.
After establishing herself in the New York art world, O'Keeffe spent substantial periods in Manhattan, where Stieglitz maintained his gallery and studio. Their apartment at the Shelton Hotel, a prominent Manhattan skyscraper, became an important domestic and artistic setting during the 1920s.
Manhattan was the center of the American modern-art network in which O'Keeffe first became widely known. Stieglitz exhibited her drawings and paintings, while writers, photographers, and artists connected to his galleries helped frame public discussions about her work.
O'Keeffe's association with Manhattan does not mean that the city was her only subject or permanent base. She also spent time at Lake George in upstate New York and later made New Mexico her home. Her paintings of flowers, skyscrapers, and natural forms emerged during different phases of this movement between urban and rural environments.